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STAT4 targets KISS1 to promote the apoptosis of ovarian granulosa cells

BACKGROUND: In mammals, it is known that the estradiol-17β (E2) is mainly synthetized in ovarian granulosa cells (GCs), and the excessive apoptosis of GCs induces the follicular atresia. Many studies have implicated the essential role of KISS1, with the pro-synthetic effect of E2 and the anti-apopto...

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Detalhes bibliográficos
Publicado no:J Ovarian Res
Main Authors: Jiang, Yao, Xin, Xiaoping, Pan, Xiangchun, Zhang, Ailing, Zhang, Zhe, Li, Jiaqi, Yuan, Xiaolong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679982/
https://ncbi.nlm.nih.gov/pubmed/33218349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-020-00741-5
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