Protein and mRNA Delivery Enabled by Cholesteryl-Based Biodegradable Lipidoid Nanoparticles

Developing safe and efficient delivery systems for therapeutic biomacromolecules is a long-standing challenge. Herein, we report a newly developed combinatorial library of cholesteryl-based disulfide bond-containing biodegradable cationic lipidoid nanoparticles. We have identified a subset of this l...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Li, Yamin, Jarvis, Rachel, Zhu, Kuixin, Glass, Zachary, Ogurlu, Roza, Gao, Peiyang, Li, Peixuan, Chen, Jinjin, Yu, Yingjie, Yang, Yongjie, Xu, Qiaobing
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679290/
https://ncbi.nlm.nih.gov/pubmed/32438474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202004994
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