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Intracellular Delivery of His-Tagged Genome-Editing Proteins Enabled by Nitrilotriacetic Acid-Containing Lipidoid Nanoparticles

Protein and peptide-based therapeutics with high tolerance and specificity along with low off-target effects and genetic risks have attracted tremendous attention during the last three decades. Herein, we report a new type of non-cationic lipidoid nanoparticle (LNP) for His-tagged protein delivery....

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Detalhes bibliográficos
Publicado no:Adv Healthc Mater
Main Authors: Li, Yamin, Li, Alice Chukun, Xu, Qiaobing
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474682/
https://ncbi.nlm.nih.gov/pubmed/30565897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201800996
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