Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds

Aptamers are short single-stranded oligonucleotides selected to bind with high affinity and specificity to a target. In contrast to antibodies, aptamers can be produced in large-scale in vitro systems without the need for any biological agents, making them highly attractive as targeting ligands for...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Omer, Marjan, Andersen, Veronica Liv, Nielsen, Jesper Sejrup, Wengel, Jesper, Kjems, Jørgen
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679244/
https://ncbi.nlm.nih.gov/pubmed/33251048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.013
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