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Defective memory engram reactivation underlies impaired fear memory recall in Fragile X syndrome
Fragile X syndrome (FXS) is an X chromosome-linked disease associated with severe intellectual disabilities. Previous studies using the Fmr1 knockout (KO) mouse, an FXS mouse model, have attributed behavioral deficits to synaptic dysfunctions. However, how functional deficits at neural network level...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7679137/ https://ncbi.nlm.nih.gov/pubmed/33215988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61882 |
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