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Optogenetic stimulation of a hippocampal engram activates fear memory recall

A specific memory is thought to be encoded by a sparse population of neurons(1,2). These neurons can be tagged during learning for subsequent identification(3) and manipulation(4,5,6). Moreover, their ablation or inactivation results in reduced memory expression, suggesting their necessity in mnemon...

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Bibliografiset tiedot
Päätekijät: Liu, Xu, Ramirez, Steve, Pang, Petti T., Puryear, Corey B., Govindarajan, Arvind, Deisseroth, Karl, Tonegawa, Susumu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331914/
https://ncbi.nlm.nih.gov/pubmed/22441246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11028
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