Urolithin A augments angiogenic pathways in skeletal muscle by bolstering NAD(+) and SIRT1

Urolithin A (UA) is a natural compound that is known to improve muscle function. In this work we sought to evaluate the effect of UA on muscle angiogenesis and identify the underlying molecular mechanisms. C57BL/6 mice were administered with UA (10 mg/body weight) for 12–16 weeks. ATP levels and NAD...

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Publicado en:Sci Rep
Autores principales: Ghosh, Nandini, Das, Amitava, Biswas, Nirupam, Gnyawali, Surya, Singh, Kanhaiya, Gorain, Mahadeo, Polcyn, Carly, Khanna, Savita, Roy, Sashwati, Sen, Chandan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678835/
https://ncbi.nlm.nih.gov/pubmed/33214614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76564-7
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