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Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia

Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid lineage cells. FLT3 is a receptor tyrosine kinase commonly overexpressed or mutated, and its mutations are associated with poo...

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Bibliografski detalji
Izdano u:J Hematol Oncol
Glavni autori: Gebru, Melat T., Wang, Hong-Gang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678146/
https://ncbi.nlm.nih.gov/pubmed/33213500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00992-1
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