Crosstalk between microglia and patient-derived glioblastoma cells inhibit invasion in a three-dimensional gelatin hydrogel model

BACKGROUND: Glioblastoma is the most common and deadly form of primary brain cancer, accounting for more than 13,000 new diagnoses annually in the USA alone. Microglia are the innate immune cells within the central nervous system, acting as a front-line defense against injuries and inflammation via...

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Publicat a:J Neuroinflammation
Autors principals: Chen, Jee-Wei Emily, Lumibao, Jan, Leary, Sarah, Sarkaria, Jann N., Steelman, Andrew J., Gaskins, H. Rex, Harley, Brendan A. C.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677841/
https://ncbi.nlm.nih.gov/pubmed/33208156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02026-6
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