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In vitro mechanical vibration down-regulates pro-inflammatory and pro-fibrotic signaling in human vocal fold fibroblasts

INTRODUCTION: Voice rest following phonotrauma or phonosurgery has a considerable clinical impact, but clinical recommendations are inconsistent due to inconclusive data. As biopsies of the vocal folds (VF) for molecular biology studies in humans are unethical, we established a new in vitro model to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hortobagyi, David, Grossmann, Tanja, Tschernitz, Magdalena, Grill, Magdalena, Kirsch, Andrijana, Gerstenberger, Claus, Gugatschka, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676657/
https://ncbi.nlm.nih.gov/pubmed/33211714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241901
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