Control of Adipocyte Thermogenesis and Lipogenesis through γ3-Adrenergic and Thyroid Hormone Signal Integration

Here, we show that β adrenergic signaling coordinately upregulates de novo lipogenesis (DNL) and thermogenesis in subcutaneous white adipose tissue (sWAT), and both effects are blocked in mice lacking the cAMP-generating G protein-coupled receptor Gs (Adipo-GsαKO) in adipocytes. However, UCP1 expres...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Guilherme, Adilson, Yenilmez, Batuhan, Bedard, Alexander H., Henriques, Felipe, Liu, Dianxin, Lee, Alexandra, Goldstein, Lauren, Kelly, Mark, Nicoloro, Sarah M., Chen, Min, Weinstein, Lee, Collins, Sheila, Czech, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676427/
https://ncbi.nlm.nih.gov/pubmed/32375048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107598
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