Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19

The COVID-19 pandemic is a worldwide health emergency which calls for an unprecedented race for vaccines and treatment. In developing a COVID-19 vaccine, we applied technology previously used for MERS-CoV to produce a prefusion-stabilized SARS-CoV-2 spike protein, S-2P. To enhance immunogenicity and...

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Publicado no:Sci Rep
Main Authors: Kuo, Tsun-Yung, Lin, Meei-Yun, Coffman, Robert L., Campbell, John D., Traquina, Paula, Lin, Yi-Jiun, Liu, Luke Tzu-Chi, Cheng, Jinyi, Wu, Yu-Chi, Wu, Chung-Chin, Tang, Wei-Hsuan, Huang, Chung-Guei, Tsao, Kuo-Chien, Chen, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676267/
https://ncbi.nlm.nih.gov/pubmed/33208827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77077-z
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