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Novel Insights Into Epigenetic Reprogramming and Destabilization of Pericentromeric Heterochromatin in Cancer

Pericentromeric heterochromatin is maintained in a condensed structure by repressive epigenetic control mechanisms and perturbation of these may cause diseases. The chromosome 1q12 region harbors the largest pericentromeric heterochromatin domain in the genome and is among the most common breakpoint...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autor Principal: Gjerstorff, Morten Frier
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674669/
https://ncbi.nlm.nih.gov/pubmed/33251148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.594163
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