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Is Crocin a Potential Anti-tumor Candidate Targeting Microtubules? Computational Insights From Molecular Docking and Dynamics Simulations

Although it is known crocin, a hydrophilic compound from the herbal plant Crocus sativus L., has promising antitumor activity, the detailed mechanism of its antitumor activity was not well understood. Recent experiments suggested tubulin as the primary target for the antitumor activity of crocin. Ho...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Wang, Ze, Ren, Juan, Jin, Nengzhi, Liu, Xingyi, Li, Xiaofei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674667/
https://ncbi.nlm.nih.gov/pubmed/33251248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.586970
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