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The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

BACKGROUND & AIMS: Liver fibrosis is a multifactorial trait that develops in response to chronic liver injury. Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl(4))-induced liver fibrosis using the Hybrid Mouse Diversity Panel, a panel of more than 100 genetically...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Tuominen, Iina, Fuqua, Brie K., Pan, Calvin, Renaud, Nicole, Wroblewski, Kevin, Civelek, Mete, Clerkin, Kara, Asaryan, Ashot, Haroutunian, Sara G., Loureiro, Joseph, Borawski, Jason, Roma, Guglielmo, Knehr, Judith, Carbone, Walter, French, Samuel, Parks, Brian W., Hui, Simon T., Mehrabian, Margarete, Magyar, Clara, Cantor, Rita M., Ukomadu, Chinweike, Lusis, Aldons J., Beaven, Simon W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674618/
https://ncbi.nlm.nih.gov/pubmed/32866618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.010
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