The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

BACKGROUND & AIMS: Liver fibrosis is a multifactorial trait that develops in response to chronic liver injury. Our aim was to characterize the genetic architecture of carbon tetrachloride (CCl(4))-induced liver fibrosis using the Hybrid Mouse Diversity Panel, a panel of more than 100 genetically...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Tuominen, Iina, Fuqua, Brie K., Pan, Calvin, Renaud, Nicole, Wroblewski, Kevin, Civelek, Mete, Clerkin, Kara, Asaryan, Ashot, Haroutunian, Sara G., Loureiro, Joseph, Borawski, Jason, Roma, Guglielmo, Knehr, Judith, Carbone, Walter, French, Samuel, Parks, Brian W., Hui, Simon T., Mehrabian, Margarete, Magyar, Clara, Cantor, Rita M., Ukomadu, Chinweike, Lusis, Aldons J., Beaven, Simon W.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674618/
https://ncbi.nlm.nih.gov/pubmed/32866618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.010
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