Rationale and design of the Medical Research Council's Precision Medicine with Zibotentan in Microvascular Angina (PRIZE) trial

Microvascular angina is caused by cardiac small vessel disease, and dysregulation of the endothelin system is implicated. The minor G allele of the non-coding single nucleotide polymorphism (SNP) rs9349379 enhances expression of the endothelin 1 gene in human vascular cells, increasing circulating c...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am Heart J
Κύριοι συγγραφείς: Morrow, Andrew J, Ford, Thomas J, Mangion, Kenneth, Kotecha, Tushar, Rakhit, Roby, Galasko, Gavin, Hoole, Stephen, Davenport, Anthony, Kharbanda, Rajesh, Ferreira, Vanessa M, Shanmuganathan, Mayooran, Chiribiri, Amedeo, Perera, Divaka, Rahman, Haseeb, Arnold, Jayanth R., Greenwood, John P., Fisher, Michael, Husmeier, Dirk, Hill, Nicholas A, Luo, Xiaoyu, Williams, Nicola, Miller, Laura, Dempster, Jill, Macfarlane, Peter W, Welsh, Paul, Sattar, Naveed, Whittaker, Andrew, Connachie, Alex Mc, Padmanabhan, Sandosh, Berry, Colin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Mosby 2020
Θέματα:
Trial Design
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674581/
https://ncbi.nlm.nih.gov/pubmed/32942043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ahj.2020.07.007
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