Anticancer Effect of Salvia plebeia and Its Active Compound by Improving T-Cell Activity via Blockade of PD-1/PD-L1 Interaction in Humanized PD-1 Mouse Model

Immune checkpoint inhibitors, increasingly used to treat malignant tumors, are revolutionizing cancer treatment by improving the patient survival expectations. Despite the high antitumor efficacy of antibody therapeutics that bind to PD-1/PD-L1, study on small molecule-based PD-1/PD-L1 inhibitors is...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Choi, Jang-Gi, Kim, Young Soo, Kim, Ji Hye, Kim, Tae In, Li, Wei, Oh, Tae Woo, Jeon, Chang Hyun, Kim, Su Jin, Chung, Hwan-Suck
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674495/
https://ncbi.nlm.nih.gov/pubmed/33224152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.598556
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