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Immune Checkpoint PD-1/PD-L1 CTLA-4/CD80 are Blocked by Rhus verniciflua Stokes and its Active Compounds

The bark of Rhus verniciflua Stokes (RVS) has been used to treat cancer in Korean herbal medicine. When we screened for PD-1 and CTLA-4 immune checkpoint inhibitors (PD-1/PD-L1 CTLA-4/CD80) from around 800 herbal extracts using competitive Enzyme-Linked Immunosorbent Assay (ELISA), we found that RVS...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Li, Wei, Kim, Tae In, Kim, Ji Hye, Chung, Hwan-Suck
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891444/
https://ncbi.nlm.nih.gov/pubmed/31717574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224062
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