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Immune Checkpoint PD-1/PD-L1 CTLA-4/CD80 are Blocked by Rhus verniciflua Stokes and its Active Compounds

The bark of Rhus verniciflua Stokes (RVS) has been used to treat cancer in Korean herbal medicine. When we screened for PD-1 and CTLA-4 immune checkpoint inhibitors (PD-1/PD-L1 CTLA-4/CD80) from around 800 herbal extracts using competitive Enzyme-Linked Immunosorbent Assay (ELISA), we found that RVS...

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Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Li, Wei, Kim, Tae In, Kim, Ji Hye, Chung, Hwan-Suck
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6891444/
https://ncbi.nlm.nih.gov/pubmed/31717574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24224062
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