Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart

PURPOSE: HFpEF (heart failure with preserved ejection fraction) is a major consequence of diabetic cardiomyopathy with no effective treatments. Here, we have characterized Akita mice as a preclinical model of HFpEF and used it to confirm the therapeutic efficacy of the mitochondria-targeted dicarbon...

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Udgivet i:Cardiovasc Drugs Ther
Main Authors: Park, Min, Nishimura, Takanori, Baeza-Garza, Carlos D., Caldwell, Stuart T., Pun, Pamela Boon Li, Prag, Hiran A., Young, Tim, Sauchanka, Olga, Logan, Angela, Forkink, Marleen, Gruszczyk, Anja V., Prime, Tracy A., Arndt, Sabine, Naudi, Alba, Pamplona, Reinald, Coughlan, Melinda T., Tate, Mitchel, Ritchie, Rebecca H., Caicci, Federico, Kaludercic, Nina, Di Lisa, Fabio, Smith, Robin A. J., Hartley, Richard C., Murphy, Michael P., Krieg, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674384/
https://ncbi.nlm.nih.gov/pubmed/32979176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-020-07086-7
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