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Maxamycins: Durable Antibiotics Derived by Rational Redesign of Vancomycin

Since its discovery, vancomycin has been used in clinic for >60 years. Because of their durability, vancomycin and related glycopeptides serve as the antibiotics of last resort for the treatment of protracted bacterial infections of resistant Gram-positive pathogens, including methicillin-resista...

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Bibliografiske detaljer
Udgivet i:Acc Chem Res
Main Authors: Wu, Zhi-Chen, Boger, Dale L.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674238/
https://ncbi.nlm.nih.gov/pubmed/33138354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.0c00569
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