A Choline-Recognizing Monomeric Lysin, ClyJ-3m, Shows Elevated Activity against Streptococcus pneumoniae

Streptococcus pneumoniae is a leading pathogen for bacterial pneumonia, which can be treated with bacteriophage lysins harboring a conserved choline binding module (CBM). Such lysins regularly function as choline-recognizing dimers. Previously, we reported a pneumococcus-specific lysin ClyJ comprisi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Luo, Dehua, Huang, Li, Gondil, Vijay Singh, Zhou, Wanli, Yang, Wan, Jia, Minghui, Hu, Shencai, He, Jin, Yang, Hang, Wei, Hongping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674022/
https://ncbi.nlm.nih.gov/pubmed/32958710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00311-20
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