ClyJ Is a Novel Pneumococcal Chimeric Lysin with a Cysteine- and Histidine-Dependent Amidohydrolase/Peptidase Catalytic Domain

Streptococcus pneumoniae is one of the leading pathogens that cause a variety of mucosal and invasive infections. With the increased emergence of multidrug-resistant S. pneumoniae, new antimicrobials with mechanisms of action different from conventional antibiotics are urgently needed. In this study...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Yang, Hang, Gong, Yujing, Zhang, Huaidong, Etobayeva, Irina, Miernikiewicz, Paulina, Luo, Dehua, Li, Xiaohong, Zhang, Xiaoxu, Dąbrowska, Krystyna, Nelson, Daniel C., He, Jin, Wei, Hongping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437478/
https://ncbi.nlm.nih.gov/pubmed/30642930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02043-18
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