STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors

Signal transducer and activator of transcription-3 (STAT3) is an oncogenic transcription factor implicated in carcinogenesis, tumor progression, and drug resistance in head and neck squamous cell carcinoma (HNSCC). A decoy oligonucleotide targeting STAT3 offers a promising anti-tumor strategy, but a...

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Publicado en:PLoS One
Autores principales: Ramasamy, Thiruganesh, Chen, Xucai, Qin, Bin, Johnson, Daniel E., Grandis, Jennifer R., Villanueva, Flordeliza S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673576/
https://ncbi.nlm.nih.gov/pubmed/33206698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242264
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