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Genome editing strategies for fetal hemoglobin induction in beta-hemoglobinopathies
Genome editing to correct a defective β-globin gene or induce fetal globin (HbF) for patients with beta-hemoglobinopathies has the potential to be a curative strategy available to all. HbF reactivation has long been an area of intense interest given the HbF inhibition of sickle hemoglobin (HbS) poly...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7673473/ https://ncbi.nlm.nih.gov/pubmed/32406490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa088 |
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