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Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning

Traces from single-molecule fluorescence microscopy (SMFM) experiments exhibit photophysical artifacts that typically necessitate human expert screening, which is time-consuming and introduces potential for user-dependent expectation bias. Here, we use deep learning to develop a rapid, automatic SMF...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Li, Jieming, Zhang, Leyou, Johnson-Buck, Alexander, Walter, Nils G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673028/
https://ncbi.nlm.nih.gov/pubmed/33203879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19673-1
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