Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

Pulmonary arterial hypertension is a severe respiratory disease characterized by pulmonary artery remodeling. RV dysfunction and dysregulated circulating metabolomics are associated with adverse outcomes in pulmonary arterial hypertension. We investigated effects of tadalafil and macitentan alone or...

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Gepubliceerd in:Pulm Circ
Hoofdauteurs: Mamazhakypov, Argen, Weiß, Astrid, Zukunft, Sven, Sydykov, Akylbek, Kojonazarov, Baktybek, Wilhelm, Jochen, Vroom, Christina, Petrovic, Aleksandar, Kosanovic, Djuro, Weissmann, Norbert, Seeger, Werner, Fleming, Ingrid, Iglarz, Marc, Grimminger, Friedrich, Ghofrani, Hossein A., Pullamsetti, Soni S., Schermuly, Ralph T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672745/
https://ncbi.nlm.nih.gov/pubmed/33240483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020947283
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