Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

Pulmonary arterial hypertension is a severe respiratory disease characterized by pulmonary artery remodeling. RV dysfunction and dysregulated circulating metabolomics are associated with adverse outcomes in pulmonary arterial hypertension. We investigated effects of tadalafil and macitentan alone or...

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Bibliografiske detaljer
Udgivet i:Pulm Circ
Main Authors: Mamazhakypov, Argen, Weiß, Astrid, Zukunft, Sven, Sydykov, Akylbek, Kojonazarov, Baktybek, Wilhelm, Jochen, Vroom, Christina, Petrovic, Aleksandar, Kosanovic, Djuro, Weissmann, Norbert, Seeger, Werner, Fleming, Ingrid, Iglarz, Marc, Grimminger, Friedrich, Ghofrani, Hossein A., Pullamsetti, Soni S., Schermuly, Ralph T.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672745/
https://ncbi.nlm.nih.gov/pubmed/33240483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020947283
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