Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats

Pulmonary arterial hypertension is a severe respiratory disease characterized by pulmonary artery remodeling. RV dysfunction and dysregulated circulating metabolomics are associated with adverse outcomes in pulmonary arterial hypertension. We investigated effects of tadalafil and macitentan alone or...

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Detaylı Bibliyografya
Yayımlandı:Pulm Circ
Asıl Yazarlar: Mamazhakypov, Argen, Weiß, Astrid, Zukunft, Sven, Sydykov, Akylbek, Kojonazarov, Baktybek, Wilhelm, Jochen, Vroom, Christina, Petrovic, Aleksandar, Kosanovic, Djuro, Weissmann, Norbert, Seeger, Werner, Fleming, Ingrid, Iglarz, Marc, Grimminger, Friedrich, Ghofrani, Hossein A., Pullamsetti, Soni S., Schermuly, Ralph T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: SAGE Publications 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672745/
https://ncbi.nlm.nih.gov/pubmed/33240483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894020947283
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