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Alignment and quantification of ChIP-exo crosslinking patterns reveal the spatial organization of protein–DNA complexes
The ChIP-exo assay precisely delineates protein–DNA crosslinking patterns by combining chromatin immunoprecipitation with 5′ to 3′ exonuclease digestion. Within a regulatory complex, the physical distance of a regulatory protein to DNA affects crosslinking efficiencies. Therefore, the spatial organi...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672471/ https://ncbi.nlm.nih.gov/pubmed/32747934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa618 |
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