EWS-FLI1 regulates and cooperates with core regulatory circuitry in Ewing sarcoma

Core regulatory circuitry (CRC)-dependent transcriptional network is critical for developmental tumors in children and adolescents carrying few gene mutations. However, whether and how CRC contributes to transcription regulation in Ewing sarcoma is unknown. Here, we identify and functionally validat...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Shi, Xianping, Zheng, Yueyuan, Jiang, Liling, Zhou, Bo, Yang, Wei, Li, Liyan, Ding, Lingwen, Huang, Moli, Gery, Sigal, Lin, De-Chen, Koeffler, H Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672457/
https://ncbi.nlm.nih.gov/pubmed/33080033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa901
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