Novel alternative ribonucleotide excision repair pathways in human cells by DDX3X and specialized DNA polymerases

Removal of ribonucleotides (rNMPs) incorporated into the genome by the ribonucleotide excision repair (RER) is essential to avoid genetic instability. In eukaryotes, the RNaseH2 is the only known enzyme able to incise 5′ of the rNMP, starting the RER process, which is subsequently carried out by rep...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Riva, Valentina, Garbelli, Anna, Casiraghi, Federica, Arena, Francesca, Trivisani, Claudia Immacolata, Gagliardi, Assunta, Bini, Luca, Schroeder, Martina, Maffia, Antonio, Sabbioneda, Simone, Maga, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672437/
https://ncbi.nlm.nih.gov/pubmed/33137198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa948
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