Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective

Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many small contributions of SNPs in the explanation of...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Frouin, Arthur, Dandine-Roulland, Claire, Pierre-Jean, Morgane, Deleuze, Jean-François, Ambroise, Christophe, Le Floch, Edith
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672157/
https://ncbi.nlm.nih.gov/pubmed/33329721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.581594
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