Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis

Systemic sclerosis (SSc) is a disease at the intersection of autoimmunity and fibrosis. However, the epigenetic regulation and the contributions of diverse cell types to SSc remain unclear. Here we survey, using ATAC-seq, the active DNA regulatory elements of eight types of primary cells in normal s...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Qian, Zaba, Lisa, Satpathy, Ansuman T., Longmire, Michelle, Zhang, Wen, Li, Kun, Granja, Jeffrey, Guo, Chuang, Lin, Jun, Li, Rui, Tolentino, Karen, Kania, Gabriela, Distler, Oliver, Fiorentino, David, Chung, Lorinda, Qu, Kun, Chang, Howard Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672105/
https://ncbi.nlm.nih.gov/pubmed/33203843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19702-z
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