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Synaptic migration and reorganization after noise exposure suggests regeneration in a mature mammalian cochlea

Overexposure to intense noise can destroy the synapses between auditory nerve fibers and their hair cell targets without destroying the hair cells themselves. In adult mice, this synaptopathy is immediate and largely irreversible, whereas, in guinea pigs, counts of immunostained synaptic puncta can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hickman, Tyler T., Hashimoto, Ken, Liberman, Leslie D., Liberman, M. Charles
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672098/
https://ncbi.nlm.nih.gov/pubmed/33203940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76553-w
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