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Protection from noise-induced cochlear synaptopathy by virally mediated overexpression of NT3
Noise exposures causing only transient threshold shifts can destroy auditory-nerve synapses without damaging hair cells. Here, we asked whether virally mediated neurotrophin3 (NT3) overexpression can repair this damage. CBA/CaJ mice at 6 wks were injected unilaterally with adeno-associated virus (AA...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6814859/ https://ncbi.nlm.nih.gov/pubmed/31653916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51724-6 |
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