Structure of the human sodium leak channel NALCN in complex with FAM155A

NALCN, a sodium leak channel expressed mainly in the central nervous system, is responsible for the resting Na(+) permeability that controls neuronal excitability. Dysfunctions of the NALCN channelosome, NALCN with several auxiliary subunits, are associated with a variety of human diseases. Here, we...

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Vydáno v:Nat Commun
Hlavní autoři: Xie, Jiongfang, Ke, Meng, Xu, Lizhen, Lin, Shiyi, Huang, Jin, Zhang, Jiabei, Yang, Fan, Wu, Jianping, Yan, Zhen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7672056/
https://ncbi.nlm.nih.gov/pubmed/33203861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19667-z
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