Nalcn Is a “Leak” Sodium Channel That Regulates Excitability of Brainstem Chemosensory Neurons and Breathing

The activity of background potassium and sodium channels determines neuronal excitability, but physiological roles for “leak” Na(+) channels in specific mammalian neurons have not been established. Here, we show that a leak Na(+) channel, Nalcn, is expressed in the CO(2)/H(+)-sensitive neurons of th...

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Pubblicato in:J Neurosci
Autori principali: Shi, Yingtang, Abe, Chikara, Holloway, Benjamin B., Shu, Shaofang, Kumar, Natasha N., Weaver, Janelle L., Sen, Josh, Perez-Reyes, Edward, Stornetta, Ruth L., Guyenet, Patrice G., Bayliss, Douglas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971364/
https://ncbi.nlm.nih.gov/pubmed/27488637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1096-16.2016
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