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Secretion of c-di-AMP by Listeria monocytogenes Leads to a STING-Dependent Antibacterial Response during Enterocolitis

Stimulator of interferon genes (STING) acts as a cytoplasmic signaling hub of innate immunity that is activated by host-derived or bacterially derived cyclic dinucleotides. Listeria monocytogenes is a foodborne, facultative intracellular pathogen that secretes c-di-AMP and activates STING, yet the i...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Louie, Alexander, Bhandula, Varaang, Portnoy, Daniel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671888/
https://ncbi.nlm.nih.gov/pubmed/33020211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00407-20
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