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Altered synaptic ultrastructure in the prefrontal cortex of Shank3-deficient rats
BACKGROUND: Deletion or mutations of SHANK3 lead to Phelan–McDermid syndrome and monogenic forms of autism spectrum disorder (ASD). SHANK3 encodes its eponymous scaffolding protein at excitatory glutamatergic synapses. Altered morphology of dendrites and spines in the hippocampus, cerebellum, and st...
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| Publicado no: | Mol Autism |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7671669/ https://ncbi.nlm.nih.gov/pubmed/33203459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-020-00393-8 |
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