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Alterations and Molecular Targeting of the GSK-3 Regulator, PI3K, in Head and Neck Cancer

Head and neck squamous cell carcinoma (HNSCC) is a highly morbid, genetically unstable disease derived from the mucoepithelium of the upper aerodigestive tract. Recent characterization of this disease has implicated the PI3K-Akt-mTOR pathway as one of the most frequently dysregulated pathways. As su...

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Vydáno v:Biochim Biophys Acta Mol Cell Res
Hlavní autoři: Lee, Michelle, Jin, Nan, Grandis, Jennifer R., Johnson, Daniel E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671657/
https://ncbi.nlm.nih.gov/pubmed/32061630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2020.118679
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