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Mathematical modeling of hepatitis C RNA replication, exosome secretion and virus release

Hepatitis C virus (HCV) causes acute hepatitis C and can lead to life-threatening complications if it becomes chronic. The HCV genome is a single plus strand of RNA. Its intracellular replication is a spatiotemporally coordinated process of RNA translation upon cell infection, RNA synthesis within a...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Zitzmann, Carolin, Kaderali, Lars, Perelson, Alan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671504/
https://ncbi.nlm.nih.gov/pubmed/33151933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008421
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