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Combined use of feature engineering and machine-learning to predict essential genes in Drosophila melanogaster

Characterizing genes that are critical for the survival of an organism (i.e. essential) is important to gain a deep understanding of the fundamental cellular and molecular mechanisms that sustain life. Functional genomic investigations of the vinegar fly, Drosophila melanogaster, have unravelled the...

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Detalhes bibliográficos
Publicado no:NAR Genom Bioinform
Main Authors: Campos, Tulio L, Korhonen, Pasi K, Hofmann, Andreas, Gasser, Robin B, Young, Neil D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671374/
https://ncbi.nlm.nih.gov/pubmed/33575603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa051
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