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Predicting gene essentiality in Caenorhabditis elegans by feature engineering and machine-learning

Defining genes that are essential for life has major implications for understanding critical biological processes and mechanisms. Although essential genes have been identified and characterised experimentally using functional genomic tools, it is challenging to predict with confidence such genes fro...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Campos, Tulio L., Korhonen, Pasi K., Sternberg, Paul W., Gasser, Robin B., Young, Neil D.
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251299/
https://ncbi.nlm.nih.gov/pubmed/32489524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.008
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