A pan-cancer analysis of HER2 index revealed transcriptional pattern for precise selection of HER2-targeted therapy

BACKGROUND: The prevalence of HER2 alterations in pan-cancer indicates a broader range of application of HER2-targeted therapies; however, biomarkers for such therapies are still insufficient and limited to breast cancer and gastric cancer. METHODS: Using multi-omics data from The Cancer Genome Atla...

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Vydáno v:EBioMedicine
Hlavní autoři: Li, Ziteng, Chen, Siyuan, Feng, Wanjing, Luo, Yixiao, Lai, Hongyan, Li, Qin, Xiu, Bingqiu, Li, Yuchen, Li, Yan, Huang, Shenglin, Zhu, Xiaodong
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670125/
https://ncbi.nlm.nih.gov/pubmed/33161227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103074
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