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CXCL13/CXCR5 signalling is pivotal to preserve motor neurons in amyotrophic lateral sclerosis
BACKGROUND: CXCL13 is a B and T lymphocyte chemokine that mediates neuroinflammation through its receptor CXCR5. This chemokine is highly expressed by motoneurons (MNs) in Amyotrophic Lateral Sclerosis (ALS) SOD1G93A (mSOD1) mice during the disease, particularly in fast-progressing mice. Accordingly...
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| Publicado no: | EBioMedicine |
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| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670099/ https://ncbi.nlm.nih.gov/pubmed/33161233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103097 |
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