Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms

Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat strains are widely used models for the most common rhodopsin gene mutation associated with the autosomal dominant form of retinitis pigmentosa. However, the mechanism(s) by...

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Vydáno v:Front Neurosci
Hlavní autoři: Kakavand, Kiana, Jobling, Andrew I., Greferath, Ursula, Vessey, Kirstan A., de Iongh, Robb U., Fletcher, Erica L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670078/
https://ncbi.nlm.nih.gov/pubmed/33224023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.581579
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