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Photoreceptor Degeneration in Pro23His Transgenic Rats (Line 3) Involves Autophagic and Necroptotic Mechanisms

Photoreceptor death contributes to 50% of irreversible vision loss in the western world. Pro23His (P23H) transgenic albino rat strains are widely used models for the most common rhodopsin gene mutation associated with the autosomal dominant form of retinitis pigmentosa. However, the mechanism(s) by...

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書誌詳細
出版年:Front Neurosci
主要な著者: Kakavand, Kiana, Jobling, Andrew I., Greferath, Ursula, Vessey, Kirstan A., de Iongh, Robb U., Fletcher, Erica L.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670078/
https://ncbi.nlm.nih.gov/pubmed/33224023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.581579
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