Modeling Resistance and Recurrence Patterns of Combined Targeted-Chemoradiotherapy Predicts Benefit of Shorter Induction Period

Optimal integration of molecularly targeted therapies such as tyrosine kinase inhibitors (TKI) with concurrent chemotherapy and radiation (CRT) to improve outcomes in genotype-defined cancers remains a current challenge in clinical settings. Important questions regarding optimal scheduling and lengt...

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Veröffentlicht in:Cancer Res
Hauptverfasser: McClatchy, David M., Willers, Henning, Hata, Aaron N., Piotrowska, Zofia, Sequist, Lecia V., Paganetti, Harald, Grassberger, Clemens
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669719/
https://ncbi.nlm.nih.gov/pubmed/32907839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3883
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