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Patient-specific tumor growth trajectories determine persistent and resistant cancer cell populations during treatment with targeted therapies

The importance of pre-existing versus acquired drug resistance in cancer patients treated with small molecule tyrosine kinase inhibitors (TKI) remains controversial. The goal of this study is to provide a general estimate of the size and dynamics of a pre-existing, drug-resistant tumor cell populati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Grassberger, Clemens, McClatchy, David, Geng, Changran, Kamran, Sophia C, Fintelmann, Florian, Maruvka, Yosef E, Piotrowska, Zofia, Willers, Henning, Sequist, Lecia V, Hata, Aaron N, Paganetti, Harald
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635042/
https://ncbi.nlm.nih.gov/pubmed/31113818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3652
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