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Soluble epoxide hydrolase as a therapeutic target for obesity-induced disorders: roles of gut barrier function involved

Emerging research supports that soluble epoxide hydrolase (sEH), an enzyme involved in eicosanoid metabolism, could be a promising target for obesity-associated disorders. The sEH enzyme is overexpressed in many tissues of obese animals. Genetic ablation or pharmacological inhibition of sEH attenuat...

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Bibliographic Details
Published in:Prostaglandins Leukot Essent Fatty Acids
Main Authors: Zhang, Jianan, Tu, Maolin, Liu, Zhenhua, Zhang, Guodong
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669660/
https://ncbi.nlm.nih.gov/pubmed/33038829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2020.102180
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